Kallikrein Cleaves C3 and Activates Complement
نویسندگان
چکیده
منابع مشابه
Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum.
The complement system is a crucial component of the innate immune response against invading bacterial pathogens. The human pathogen Neisseria meningitidis (Nm) is known to possess several mechanisms to evade the complement system, including binding to complement inhibitors. In this study, we describe an additional mechanism used by Nm to evade the complement system and survive in human blood. U...
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Complement is one of the first host defense barriers against bacteria. Activated complement attracts neutrophils to the site of infection and opsonizes bacteria to facilitate phagocytosis. The human pathogen Staphylococcus aureus has successfully developed ways to evade the complement system, for example by secretion of specific complement inhibitors. However, the influence of S. aureus proteas...
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ژورنال
عنوان ژورنال: Journal of Innate Immunity
سال: 2017
ISSN: 1662-811X,1662-8128
DOI: 10.1159/000484257